Fred Hutchinson Cancer Research Center | Seattle, WA
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This is a multi-center study to compare the efficacy and safety of itolizumab versus placebo as first-line therapy for subjects with Grade III-IV aGVHD or Grade II with LGI involvement, in combination with corticosteroids
Full description
This study will enroll 200 subjects at approximately 125 sites globally. Subjects will be randomized in a 1:1 ratio to active or placebo and will receive a total of 7 doses administered intravenously approximately every 2 weeks. The study follows the patients for a total of approximately 365 days.
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Primary purpose
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Interventional model
Masking
200 participants in 2 patient groups, including a placebo group
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Clinical Trial Manager
Data sourced from clinicaltrials.gov
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