A Study of Minimally Invasive Proximal Gastrectomy Versus Minimally Invasive Total Gastrectomy for Gastric and Gastroesophageal Junction Cancers

Memorial Sloan Kettering Cancer Center (MSK)

Status: Active, not recruiting

Conditions: Gastric Cancer; GastroEsophageal Cancer; Gastroesophageal Junction Adenocarcinoma

Treatments: Other: MDASI-GI

Study type: Observational

Funder types: Other

Identifiers

NCT06243757

23-324

Details and patient eligibility

About

Participants will a diagnosis of gastroesophageal junction (GEJ) adenocarcinoma and will have either a minimally invasive proximal gastrectomy (MIPG) or a minimally invasive total gastrectomy (MITG) as part of their routine care. Participants with complete a questionnaire 1 month before the surgical procedure and then 1, 3, 6 and 12 months after the surgical procedure.

Enrollment: 4 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Able to speak and read English, Spanish, Japanese or Korean
• Patients with a biopsy-confirmed diagnosis of non-metastatic gastric or GEJ adenocarcinoma, who are scheduled to undergo MIPG or MITG for curative-intention
• Age ≥ 18

Exclusion criteria

• Patients with known malabsorption syndromes or a lack of physical integrity of the upper gastrointestinal tract
• Patients with known narcotic dependence, with average daily dose > 5 mg oral morphine equivalent
• Subjects deemed unable to comply with study and/or follow-up procedures, at investigators' discretion
• Patients who are pregnant (since are excluded from receiving standard-of-care MIPG or MITG)

Trial design

4 participants in 2 patient groups

Minimally Invasive Proximal Gastrectomy/MIPG

Description:

Participants will undergo MIPG (Trial Procedure)

Treatment:

Other: MDASI-GI

Minimally Invasive Total Gastrectomy/MITG

Description:

Participants will undergo MITG (Standard of Care/Control Group)

Treatment:

Other: MDASI-GI