A Study of Noninvasive Methods to Evaluate Skin and Mucosal Conditions

Memorial Sloan Kettering Cancer Center (MSK)

Status

Enrolling

Conditions

Skin Lesion

Mucosal Lesion

Treatments

Diagnostic Test: Ultrasound

Diagnostic Test: Hyperspectral imaging

Diagnostic Test: Patient self-imaging

Diagnostic Test: 3-dimensional total body photography

Diagnostic Test: Electrical impedance spectroscopy

Diagnostic Test: Optical Coherence Tomography imaging

Diagnostic Test: Confocal microscopy

Diagnostic Test: Dermoscopic imaging

Study type

Observational

Funder types

Other

Identifiers

NCT04743362

21-019

Details and patient eligibility

About

The purpose of this study is to find out whether using noninvasive methods to study the appearance of lesions can improve diagnostic accuracy before a biopsy is required and help guide treatment planning. The database created to store these images is called an Image Repository, and it will be used to support clinical practice, teaching and training, and future research.The High-resolution OCT (Apollo Medical Optics) device ApolloVue® S100 Image System (medical device Class II) can provide both cross-sectional and en-face images with cellular information.

Enrollment

5,010 estimated patients

Sex

All

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

All ages
Patients with a muco-cutaneous lesion(s) amenable to imaging by non-invasive tools
Healthy volunteer subjects
Ability to give informed consent or in the case of pediatric patients, assent and consent from the parent/guardian

Exclusion criteria

Allergy or intolerance to ultrasound gel or mineral oil used for imaging
Patients who are not able to comply with imaging procedure

Trial design

5,010 participants in 1 patient group

Participants with muco-cutaneous lesions

Description:

Participants will have muco-cutaneous lesions for non-invasive evaluation (including normal skin or mucosa and benign lesions) and will be identified by their physicians or fellows during routine clinical care.

Treatment: