A Study of Paravertebral Block in Thoracic Outlet Syndrome

Mayo Clinic

Status and phase: Invitation-only; Phase 4

Conditions: Thoracic Outlet Syndrome

Treatments: Drug: Ropivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT05544721

22-006685

Details and patient eligibility

About

This research is being done to evaluate the effects of receiving only a paravertebral block prior to first rib resection procedure versus receiving the block both pre and post procedure.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

- All Thoracic Outlet Syndrome patients scheduled for first rib resection surgery.

Exclusion criteria

• Patients who are pregnant.
• Patients with prior first rib resection on side of presentation.
• Patients with complex regional pain syndrome (CRPS).
• Patients with brachial plexus disorder.
• Patients with cervical rib.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

Paravertebral block pre procedure

Active Comparator group

Description:

Subjects will receive a preoperative paravertebral block only

Treatment:

Drug: Ropivacaine

Paravertebral block pre and post procedure

Active Comparator group

Description:

Subjects will receive one paravertebral block, administered preoperatively and one paravertebral block, administered on postoperative day 1

Treatment:

Drug: Ropivacaine