A Study of Rofecoxib in the Treatment of Post-Operative Pain After Total Knee Joint Replacement (0966-259)

Merck Sharp & Dohme (MSD)

Status and phase: Terminated; Phase 4

Conditions: Pain

Treatments: Drug: Comparator: diclofenac 2x 75 mg; Drug: MK0966; rofecoxib

Study type: Interventional

Funder types: Industry

Identifiers

NCT00140920

0966-259

2005_054

Details and patient eligibility

About

A study to compare pre-operative administration of rofecoxib versus post-operative administration of diclofenac or rofecoxib, respectively, in the treatment of post-operative pain after total knee joint replacement in patients with osteoarthritis of the knee.

Enrollment: 11 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Males or females at least 18 years of age who have osteoarthritis of the knee and have undergone total knee joint replacement.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind