A Study of Sex Differences in Neurocirculatory Control

Mayo Clinic

Status: Enrolling

Conditions: Obstructive Sleep Apnea

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT06261034

23-008765

8K12AR084222-15 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The purpose of this study is to investigate potential sex differences in neurocirculatory control of blood pressure in patients with untreated obstructive sleep apnea (OSA).

Enrollment: 60 estimated patients

Sex: All

Ages: 20 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 20-70 years of age

Exclusion criteria

• Coronary artery disease
• Heart failure
• Pregnancy
• COPD
• Diabetes
• CKD
• Sleep disorders other than OSA
• Shift workers
• Individuals who typically go to sleep after midnight
• Individuals who traveled across ≥2 time zones within one week of study visits
• BMI ≥40.0kg/m2
• Use of nicotine-containing products within the two years preceding study visits
• Use of allopurinol, proton pump inhibitors, or other medications/supplements which interfere with outcome measures