A Study of Structure and Function of Radial Artery After Transradial Coronary Intervention

The First Hospital of Qinhuangdao

Status: Completed

Conditions: Intervention; Transradial

Treatments: Procedure: Percutaneous coronary intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT02831322

21735

Details and patient eligibility

About

Several approaches have been proposed to reduce the risk of RAO, including anticoagulation, immediate postprocedural sheath removal, and a small sheath/radial artery ratio. Doppler ultrasound examination showed that interrupted blood flow in RA tend to occur in the proximal end rather than distal part of the artery,which was ignored by a majority of interventional cardiologists. Different insights into occlusion location may lead to different options of sheath materials, models, catheters and puncture access. Thus, the investigators designed this present study to explore the reason of radial artery endothelial dysfuction and damage and occlusion location by flow-mediated dilation (FMD) to determine the suitable method to reduce occlusion risk during TRI.

Enrollment: 600 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• admitted for transradial catheterization.

Exclusion criteria

• femoral access, arterial circulatory disease, pathological Allen tests, decompensated heart failure, chronic renal failure

Trial design

Primary purpose: Prevention

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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600 participants in 2 patient groups

radial artery occlusion

Experimental group

Description:

Radial artery occlusion was the absence of a flow signal by Doppler ultrasound examination.

Treatment:

Procedure: Percutaneous coronary intervention

radial artery normal

Other group

Description:

Radial artery normal was blood flow signal by Doppler ultrasound

Treatment:

Procedure: Percutaneous coronary intervention