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A Study of the Association Between Tobacco Smoking and Bipolar Affective Disorder

T

Tirat Carmel Mental Health Center

Status

Completed

Conditions

Bipolar Disorder

Study type

Observational

Funder types

Other

Identifiers

NCT00741299
GKN2007

Details and patient eligibility

About

The purpose of this study is to examine whether tobacco smoking is associated with bipolar affective disorder (severity of depressive and manic symptoms, presence of psychotic symptoms, history of a suicide attempts and other clinical features.)

Full description

An association exists between smoking and schizophrenia, independent of other factors and related to psychotic symptomatology. Only a few small descriptive studies have examined the prevalence and correlates of tobacco use among bipolar patients with conflicting results. Patients who smoke score higher on rating scales for psychotic symptoms than their non-smoking peers. While the association of smoking with psychotic symptomatology in schizophrenia is established, such association according to bipolar affective disorder has been reported in a few studies and remains unclear. Also a few studies reported about association of smoking with depressive and manic symptoms, and with suicidal behavior in bipolar patients. Thus further investigation of these issues is warranted.

Enrollment

100 patients

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Age 18-65 male or female
  • DSM -IV criteria for bipolar I affective disorder
  • Ability and willingness to sign informed consent for participation in the study

Exclusion criteria

  • Unwillingness or inability to participate in the study

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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