A Study of the Effect on Oro-dental Complications of Intensity Modulated Radiotherapy (IMRT) Versus Conventional Radiotherapy in Patients With Cancer of the Head or Neck

Ghent University Hospital (UZ)

Status: Completed

Conditions: Cancer: Head or Neck

Treatments: Procedure: IMRT versus conventional radiotherapy

Study type: Interventional

Funder types: Other

Identifiers

NCT00323466

2006/164

Details and patient eligibility

About

Study to investigate the effect of two types of radiotherapy on saliva: IMRT versus conventional radiotherapy.

In each group, one part will receive normal dental preventive treatment. The other part will use products for treatment of dry mouth (Biotene gamma).

Both anorganic and organic components of the saliva will be studied at different time points, combined with bacterial swabs.

Enrollment: 43 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• > 18 years old
• Cancer of head or neck

Exclusion criteria

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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43 participants in 1 patient group

IMRT

Experimental group

Treatment:

Procedure: IMRT versus conventional radiotherapy