A Study of the Effects of Fish Protein Intake on Glucose Regulation in Overweight and Obese Adults. (FISK3)

University of Bergen

Status: Completed

Conditions: Overweight; Obesity

Treatments: Dietary Supplement: Cod protein; Dietary Supplement: Herring protein hydrolysate; Dietary Supplement: Milk protein; Dietary Supplement: Salmon protein hydrolysate

Study type: Interventional

Funder types: Other

Identifiers

NCT01641055

2011/572

Details and patient eligibility

About

The purpose of this study is to compare the possible health benefits of intake of proteins from salmon, herring, cod and milk on glucose tolerance in overweight and obese adults. Overweight and obese subjects often have reduced glucose tolerance, and previous findings from a study on cod proteins suggested that glucose tolerance was improved.

Full description

Participants receive 2.5g protein per day for 8 weeks as tablets.

Enrollment: 93 patients

Sex: All

Ages: 18 to 69 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI above 27 kg/m2
• healthy

Exclusion criteria

• fasting blood glucose above 7 mM
• medication that affects blood glucose, lipids and inflammatory status
• pregnancy or breastfeeding
• allergies to fish or milk
• intentional weight loss and large fluctuation in body weight
• a high consumption of fish
• an extreme diet
• use of fish oil, n-3 or multivitamin supplements

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Double Blind

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93 participants in 4 patient groups, including a placebo group

Salmon protein hydrolysate

Experimental group

Treatment:

Dietary Supplement: Salmon protein hydrolysate

Herring protein hydrolysate

Experimental group

Treatment:

Dietary Supplement: Herring protein hydrolysate

Cod protein

Sham Comparator group

Treatment:

Dietary Supplement: Cod protein

Milk protein

Placebo Comparator group

Treatment:

Dietary Supplement: Milk protein