A Study Of The Efficacy Of Atorvastatin For Lowering Cholesterol In High-Risk Patients With High Cholesterol

Viatris

Status and phase: Completed; Phase 4

Conditions: Dyslipidemias

Treatments: Drug: Atorvastatin

Study type: Interventional

Funder types: Industry

Identifiers

NCT00644670

A2581099

Details and patient eligibility

About

The purpose of the study is to evaluate the effectiveness of atorvastatin in lowering cholesterol and getting these high risk patients to their goals of LDL <115 mg/dl across starting doses of 10 mg, 20 mg, or 40 mg with one step titration.

Enrollment: 232 patients

Sex: All

Ages: 30 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Dyslipidemia
• At a high risk for coronary heart disease

Exclusion criteria

• Use of higher than usual maintenance doses of statin drugs at screening
• Uncontrolled diabetes or high blood pressure
• Impaired liver function

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

232 participants in 2 patient groups

Previous Treatment with a Usual Maintenance Dose of a Statin

Experimental group

Treatment:

Drug: Atorvastatin

Drug: Atorvastatin

Statin-Naive

Experimental group

Treatment:

Drug: Atorvastatin

Drug: Atorvastatin