A Study of the Intervention Effect of a Hybrid Exercise Program on Elderly With Sarcopenia

Northeast Normal University

Status: Completed

Conditions: Sarcopenia

Treatments: Behavioral: Taichi exercise and resistance training; Behavioral: resistance training; Behavioral: Randomly selected exercise program; Behavioral: self-determine sequence exercise program

Study type: Interventional

Funder types: Other

Identifiers

NCT05694117

CCEE2019

Details and patient eligibility

About

Sarcopenia is a geriatric condition characterized by a progressive decrease in skeletal muscle content and loss of muscle function. Resistance exercise, Taichi exercise and the hybrid exercise program consisting of the two aforementioned methods have been demonstrated could increase the skeletal muscle mass of the elderly with sarcopenia. However, note that the above contents may be performed in a different order in a treatment, equally important but less well understood is the sequence in which it should be performed. Surprisingly, the exercise sequence has not been comprehensively investigated. Therefore, investigators designed a self-ordered exercise program combining resistance exercise, tai chi and a hybrid exercise program to investigate whether the decline in skeletal muscle area could be better overcome and the reversal of sarcopenia in elderly with sarcopenia.

Enrollment: 392 patients

Sex: All

Ages: 60 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. satisfied the Asian screening criteria for sarcopenia by the Asian Working Group for Sarcopenia;
2. age higher than 60 but less than 75 years of age.

Exclusion criteria

1. with serious illness or breathing failure;
2. with neuro-muscular diseases;
3. taking medication that has an effect on the function of skeletal muscles;
4. with conditions relating to the neurological system or the mental health;
5. in another scheduled training plan.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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392 participants in 5 patient groups

self-determine sequence exercise program

Experimental group

Description:

The trial was divided into three cycles, and participants were allowed to choose any one of the a Taichi exercise program, a hybrid program of Taichi exercise and resistance training programs, and resistance training as their intervention content before the start of each cycle. Participants who chose Taichi exercise performed one hour of Taichi exercise for each session, while participants who chose a hybrid exercise program of Taichi exercise and resistance training completed Taichi exercise in the first half hour and resistance training for the second half hour. Participants who chose resistance training performed one hour of resistance training. One hour per training session, three times a week for 24 weeks

Treatment:

Behavioral: self-determine sequence exercise program

resistance training

Experimental group

Description:

Resistance strength training for resistance exercise and aimed at promoting the greatest hypertrophy response. Training is divided into three cycles, with progressive training load. Resistance exercise intervention three times a week for 24 weeks, one hour each time.

Treatment:

Behavioral: resistance training

control group

No Intervention group

Description:

The participants in the control group were introduced by nurses to education about sarcopenia and various methods for preventing it, such as consuming more protein through their diet and participating in greater physical exercise.

Taichi exercise and resistance training

Experimental group

Description:

The trial was divided into three cycles, each lasting eight weeks. Participants performed a hybrid program of Taichi exercise and resistance training of varying duration and intensity in each cycle. Each session lasted one hour, three times a week for 24 weeks.

Treatment:

Behavioral: Taichi exercise and resistance training

Randomly selected exercise program

Experimental group

Description:

The trial was divided into three cycles, and participants were allowed to choose any one of the a Yijinjing exercise program, a hybrid program of Yijinjing exercise and resistance training programs, and resistance training as their intervention content before the start of each cycle. Participants who chose Yijinjing exercise performed one hour of Yijinjing exercise for each session, while participants who chose a hybrid exercise program of Yijinjing exercise and resistance training completed Yijinjing exercise in the first half hour and resistance training for the second half hour. Participants who chose resistance training performed one hour of resistance training. One hour per training session, three times a week for 24 weeks

Treatment:

Behavioral: Randomly selected exercise program