A Study of the Mechanisms by Which Mood and Sleep Disorders Interact (mechanisms)

Shandong University

Status: Invitation-only

Conditions: Sleep Disorder Insomnia Chronic

Treatments: Other: General clinical information; Other: electrocardiographic/magnetic and electroencephalographic/magnetic monitoring data; Diagnostic Test: ambulatory electrocardiogram; Other: scale assessment

Study type: Observational

Funder types: Other

Identifiers

NCT07495189

KYLL-202408-063-1

Details and patient eligibility

About

The main purpose of the study is to explore the mechanisms by which mood and sleep disorders interact. The exploratory aim of this study is to discover the relationship between ECG/MCG and EEG/MEG characteristics and mood and sleep disorders and to discover the correlation between cardio-brain monitoring and to explore the mechanisms by which mood and sleep disorders influence each other.

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

1.Normal health group2.Mood disorders with insomnia group3.Mood disorders without insomnia group4.Primary insomnia group

Trial design

200 participants in 4 patient groups

Mood disorder with insomnia group

Description:

* Meet the above diagnostic criteria for insomnia * Age 18-80 years old * PSQI\>5, ISI\>7, HAMA\>7 and/or HAMD≥7 ④No communication barriers ⑤Signed informed consent form

Treatment:

Other: scale assessment

Diagnostic Test: ambulatory electrocardiogram

Other: electrocardiographic/magnetic and electroencephalographic/magnetic monitoring data

Other: General clinical information

Primary insomnia group

Description:

①meet the above diagnostic criteria for insomnia * don't meet the above diagnostic criteria for mood disorders * age 18～80 years old * PSQI\>5, ISI\>7, HAMA≤7, and HAMD\<7 ⑤no communication barriers ⑥sign the informed consent form

Treatment:

Other: scale assessment

Diagnostic Test: ambulatory electrocardiogram

Other: electrocardiographic/magnetic and electroencephalographic/magnetic monitoring data

Other: General clinical information

Normal healthy group

Description:

physical, mental, psychological and social relations are in perfect condition

Treatment:

Other: scale assessment

Diagnostic Test: ambulatory electrocardiogram

Other: electrocardiographic/magnetic and electroencephalographic/magnetic monitoring data

Other: General clinical information

Mood disorder without insomnia group

Description:

* do not meet the above diagnostic criteria for insomnia ② age 18 - 80 years * PSQI ≤ 5, ISI ≤ 7, HAMA \> 7 and/or HAMD ≥ 7 ④ no communication barriers ⑤ signed informed consent form

Treatment:

Other: scale assessment

Diagnostic Test: ambulatory electrocardiogram

Other: electrocardiographic/magnetic and electroencephalographic/magnetic monitoring data

Other: General clinical information