A Study of Two Forms of Pentamidine in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS

LyphoMed

Status: Completed

Conditions: Pneumonia, Pneumocystis Carinii; HIV Infections

Treatments: Drug: Pentamidine isethionate

Study type: Interventional

Funder types: Industry

Identifiers

NCT00002292

88-001

023B

Details and patient eligibility

About

To compare parenteral versus inhaled pentamidine in patients with documented Pneumocystis carinii pneumonia (PCP) with AIDS.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Exclusion Criteria

Co-existing Condition:

Patients with the following are excluded:

• Previous history of adverse reaction to pentamidine.
• History of asthma.
• Pulmonary Kaposi's sarcoma.

Patients with the following are excluded:

• Previous history of adverse reaction to pentamidine.
• History of asthma.
• Pulmonary Kaposi's sarcoma.
• Inability to understand the consent procedure.

All patients hospitalized at Cedars-Sinai Medical Center with AIDS and possible Pneumocystis carinii pneumonia (PCP) will be eligible.

• Patients with HIV antibody or AIDS and a clinical presentation suggesting PCP are eligible.