A Study on the Effect of Position on Walking Labour Epidural Efficacy

University of Saskatchewan

Status: Unknown

Conditions: Labor Pain; Analgesia, Epidural

Treatments: Procedure: Lumbar Epidural

Study type: Interventional

Funder types: Other

Identifiers

NCT04469101

Bio 1813

Details and patient eligibility

About

This study is being done to better understand how patient positioning can affect pain relief after an epidural. In addition to pain, the investigators will assess how position affects epidural spread, and its effects on maternal blood pressure and fetal heart rate.

Full description

Epidurals will be placed with parturients in the standard sitting position. An epidural catheter will be placed to a depth of 5 cm into the epidural space. After placement, parturients will be randomized to one of the four position groups (left uterine displacement, left lateral, right lateral, or seated upright). After successful positioning, a series of 5 cc bolus doses of 0.08% ropivacaine with 2 mcg per cc of fentanyl will be injected through the epidural catheter in 5 minute intervals for a total volume of 20 cc. After the initial loading dose of epidural solution has been injected in the first 20 minutes post-insertion, the patient will be able to return to whatever position they are most comfortable with. The parturient will be asked to rate their pain on a verbal pain scale of between 0 and 10 at the peak of their contraction at three time intervals. The spread of the blockade will be assessed with ice applied along both the left and right mid-clavicular lines. Maternal blood pressure will be measured on the upper arm in all patients as per nursing protocol. Fetal heart rate will be monitored intermittently with Doppler ultrasound as per nursing protocol.

Enrollment: 216 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Active labour or admitted for induction of labour
• Requesting an epidural for labour analgesia
• Contractions occurring greater than once every 5 minutes

Exclusion criteria

• Coagulation disorder
• High risk pregnancy as per obstetrics
• Spinal pathology (included scoliosis, herniated disks, or previous lumbar back surgery)

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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216 participants in 4 patient groups

Left Uterine Displacement

Experimental group

Description:

Supine with left tilt for uterine displacement

Treatment:

Procedure: Lumbar Epidural

Left Lateral

Experimental group

Description:

Left lateral decubitus position

Treatment:

Procedure: Lumbar Epidural

Right Lateral

Experimental group

Description:

Right lateral decubitus position

Treatment:

Procedure: Lumbar Epidural

Upright

Experimental group

Description:

Upright seated position

Treatment:

Procedure: Lumbar Epidural