A Study on the Intervention of Metabolic Syndrome Patients With Exercise Prescription Based on Ventilatory Threshold Using Cardiopulmonary Exercise Test

Taiyuan Central Hospital of Shanxi Medical University

Status

Completed

Conditions

Metabolic Syndrome X

Treatments

Behavioral: the ventilatory threshold individualized group

Behavioral: the maximum physiological value standardized group

Study type

Interventional

Funder types

Other

Identifiers

NCT06379204

No.2022026

Details and patient eligibility

About

Analyze the clinical intervention effects and differences of progressive precision exercise prescriptions formulated by two methods for determining exercise intensity on metabolic syndrome (MS). Compare the effects of the two on the cardiovascular endurance of the MS population and verify the effectiveness of individualized methods in reducing absolute exercise intensity for MS patients.

Enrollment

52 patients

Sex

All

Ages

25 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients were included who met the Chinese Diabetic Society diagnostic criteria for MS-i.e., three or more of the following five items: (i) abdominal obesity (i.e., central obesity) with waist circumference ≥ 90 cm in males and ≥ 85 cm in females; (ii) hyperglycemia defined as fasting blood glucose ≥ 6.1 mmol/L or blood glucose ≥ 7.8 mmol/L two hours after glucose loading, or diagnosis of diabetes mellitus; (iii) hypertension defined as blood pressure ≥ 130/85 mmHg or diagnosed with hypertension; (iv) fasting triglycerides (TG) ≥ 1.70 mmol/L; and (v) fasting high-density lipoprotein cholesterol (HDL-C) &lt; 1.04 mmol/L.
Patients were aged 25 to 65 years, with no restrictions on number of males or females.
Patients exhibited a long-term sedentary lifestyle and did not carry out moderate-intensity physical activity for at least three d/week of 30 min/d duration within three months of the study.
Patients were willing to participate and sign the informed consent form.

Exclusion criteria

Patients in an acute phase of various diseases or with organ failure, tumor, myocardial infarction, cardiac insufficiency, myocarditis, or chronic lung disease;
Patients with long-term alcohol consumption and those unable to ensure regular lifestyle habits during the intervention period;
Patients who were unable to ensure that they would carry out the stipulated exercise protocol during the intervention; and
Patients with drug modifications during the intervention that could affect the outcome markers.