A Study on the Pain Control Effect of the Anesthetic Method During Prostate Biopsy: Comparison Between Pelvic Plexus Block and Periprosthetic Nerve Block

Yonsei University Health System (YUHS)

Status: Unknown

Conditions: Transrectal Systematic Prostate Biopsy Related Pain

Treatments: Procedure: Pelvic plexus block; Procedure: Periprostatic nerve block

Study type: Interventional

Funder types: Other

Identifiers

NCT03681522

3-2018-0211

Details and patient eligibility

About

This study assesses differences in the effects of pelvic plexus block and periprostatic nerve block among various anesthetic methods that reduce the pain caused by prostate biopsy.

Full description

Recently, various types of local anesthetic methods have been attempted to reduce biopsy-related pain leading to changes in the type of anesthetic agents and site of injection. Of these anesthetics and combinations, pelvic plexus block and periprostatic nerve block seem to be the very effective way to control prostate biopsy-related pain. However, few studies have compared these two methods.

Enrollment: 58 estimated patients

Sex: Male

Ages: 50+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• abnormal prostate finding on digital rectal examination
• serum PSA level of > 2.5 ng/mL
• Transrectal ultrasonographic abnormal lesion

Exclusion criteria

• under 50 years old
• a history of previous TRUS-guided biopsy
• chronic prostatitis/pelvic pain
• neurological conditions (dementia, Parkinson disease, or cerebral infarction)
• bleeding diathesis
• active UTI
• hemorrhoids/anal fissure/anal fistula
• known allergy to lidocaine

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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58 participants in 2 patient groups

Pelvic plexus block

Experimental group

Description:

The injections of 2.5 mL of 2% lidocaine were made to the pelvic neurovascular plexus located at the end of the seminal vesicle under Doppler US guidance on each side

Treatment:

Procedure: Pelvic plexus block

Periprostatic nerve block

Active Comparator group

Description:

The injections of 2.5 mL of 2% lidocaine were made to the neurovascular bundles at the junction of the prostate-bladder-seminal vesicle.

Treatment:

Procedure: Periprostatic nerve block