A Study on the Possible Health Effects of Lean Fish and Fatty Fish Intake in Overweight or Obese Adults (FISK2)

University of Bergen

Status: Completed

Conditions: Overweight; Obesity

Treatments: Other: Fatty fish; Other: Lean fish

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT02350595

FISK2

Details and patient eligibility

About

The potential health effects of high intake of lean or fatty fish will be investigated in overweight or obese adults. Participants consume 750g/week of fillets of fish for 8 weeks.

Hypothesis:

High intake of fatty or lean fish will beneficially affect glucose regulation and the immune system.

Enrollment: 76 patients

Sex: All

Ages: 18 to 69 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI ≥27 kg/m2
• fasting blood glucose ≤7.0 mmol/L

Exclusion criteria

• pregnancy
• incompatibility with fish consumption (allergies, intolerance and/or dislike)
• diagnosed diabetes mellitus, heart disease or gastrointestinal diseases
• use of medications affecting lipid metabolism or glucose homeostasis
• use of anti-inflammatory medications
• use of supplements containing long chain n-3 fatty acids
• intentional weight loss
• and large fluctuation in body weight (>3 kg) over the previous two months

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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76 participants in 3 patient groups

Lean fish

Experimental group

Description:

Participants eat 750g of lean fish per week for 8 weeks.

Treatment:

Other: Lean fish

Fatty fish

Experimental group

Description:

Participants eat 750g of fatty fish per week for 8 weeks.

Treatment:

Other: Fatty fish

Control

No Intervention group

Description:

Participants eat as normal, but avoid fish and seafood for 8 weeks.