A Study on the Verification of Kidney CT Non-inferiority Using Low Concentration Contrast Agent

Seoul National University

Status

Enrolling

Conditions

Renal Disease

Treatments

Diagnostic Test: Contrast enhanced Kidney CT

Study type

Observational

Funder types

Other

Industry

Identifiers

NCT05831943

SNUH-2022-0218

Details and patient eligibility

About

This prospective study aims to evaluate clinical usefulness of low-voltage renal CT using low-concentration contrast agent and to compare with existing imaging techniques.

Enrollment

88 estimated patients

Sex

All

Ages

19 to 80 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Subjects with no abnormalities in renal function (Serum creatinine < 1.4 mg/dl , GFR > 45mL/min/1.73 m2) in blood tests performed within one month
Those who understand the contents of the research subject explanation and voluntarily sign the consent form

Exclusion criteria

Body mass index > 30
Subjects whose renal function abnormality was confirmed in a blood test (Serum creatinine > 1.4 mg/dl , GFR < 45mL/min/1.73 m2) conducted within one month
Diabetic patients taking metformin
Those with a history of urinary tract obstruction
Those with a history of bladder, urinary tract, or kidney surgery that may affect the evaluation of the contrast agent in the renal parenchyma
Those whose anatomical deformities have been identified in previous images that may interfere with image analysis
Those who know or have been reported to have a history of contrast agent side effects in previous CT scans
Those with a history of hypersensitivity or adverse reactions to iobrix (intravascular CT contrast) or iodine based agent
Those with severe thyroid disease
Pregnancy
Those who are judged unsuitable for clinical trials by the researcher for reasons such as having other severe diseases or being judged to have a high risk of adverse reactions to intravascular contrast agents