A Study to Compare Genetic Variations of IGF-I and IGF-II

Avera McKennan Hospital & University Health Center

Status

Completed

Conditions

Dementia

Study type

Observational

Funder types

Other

Identifiers

NCT01329523

AIHBG-1370-IGF

Details and patient eligibility

About

The purpose of this study is to determine if insulin-like growth factors (IGF) play a role in the development of dementia, specifically Alzheimer's disease (AD). The study will compare results from genetic testing between patients with AD and two other groups: younger biological family members of the AD patients and individuals without AD matched by age to the AD patients.

Enrollment

50 patients

Sex

All

Ages

50 to 81 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Men and women between the ages of 50 and 81 years old who have a diagnosis of dementia
Men and women who are at least 18 years old and are biologically related to the study subject with dementia
Control subjects must not have a diagnosis of dementia and must be matched in age to the study subjects with dementia

Exclusion criteria

Biological family members of the dementia patient who are either younger than 17 years of age or older than the patient with dementia
Biological family members with a diagnosis of dementia
Age-matched control subjects with a diagnosis of dementia