A Study to Compare the Effectiveness of Different High-intensity Interval Training Programs in Cardiac Rehabilitation

Mayo Clinic

Status: Active, not recruiting

Conditions: Cardiac Rehabilitation

Treatments: Other: Progressive High Intensity Interval Training (PRO-HIIT); Other: Constant High Intensity Interval Training (CON-HIIT)

Study type: Interventional

Funder types: Other

Identifiers

NCT04555512

20-005923

Details and patient eligibility

About

The purpose of the study is to examine the effect of two different high intensity interval training (HIIT) prescription approaches on improving fitness, heart function, and the ability of the body's muscles to receive oxygen.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult 18 years and older.
• English speaking.
• Able to provide consent.
• Has a qualifying indication for center-based cardiac rehabilitation that is non-surgical (i.e., Acute coronary syndrome, myocardial infarction, percutaneous coronary intervention, and stable angina).

Exclusion criteria

• Participants referred to cardiac rehabilitation following coronary artery bypass surgery, heart valve repair/replacement, heart transplant, or those with ventricular assist devices.
• Patients who are unable to engage in a regularly structured exercise training program as part of a clinically indicated center-based outpatient cardiac rehabilitation program are not eligible.
• Patients unable/unwilling to provide informed consent will not be enrolled.
• Patients identified as having a contraindication to high intensity exercise.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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30 participants in 2 patient groups

Standard-care interval-training group

Active Comparator group

Description:

Subjects will complete a standard interval-training program that remains constant for the entire 12 weeks of cardiac rehabilitation.

Treatment:

Other: Constant High Intensity Interval Training (CON-HIIT)

Progressive interval-training group

Experimental group

Description:

Subjects will complete an interval-training program during which the number of intervals and the duration of each interval are changed across the 12-week cardiac rehabilitation program.

Treatment:

Other: Progressive High Intensity Interval Training (PRO-HIIT)