A Study to Compare Two Rehabilitation Protocols for Knee Osteoarthritis

Ente Ospedaliero Cantonale, Bellinzona

Status

Enrolling

Conditions

Knee Osteoarthritis

Treatments

Other: Anti-gravity treadmill

Other: Blood flow restriction training + Anti-gravity treadmill

Study type

Interventional

Funder types

Other

Identifiers

NCT05728827

ORL-ORT-39

Details and patient eligibility

About

The aim of this randomized controlled study is to investigate whether the implementation of Blood Flow Restriction, in which the de-loading factor is delivered by the combined progressive de-loaded walking to running activity on an antigravity treadmill (treatment group), is more effective than the same antigravity protocol alone (control group).

Participants will be divided as follows:

Intervention group: anti-gravity treadmill combined with blood flow restriction Control group: anti-gravity treadmill Both groups will also undergo a standardized knee Osteoarthritis management through an aerobic and strength program.

Enrollment

70 estimated patients

Sex

All

Ages

45 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age included between 45 and 80 years old
Patients with knee OA diagnosed by a medical doctor with a radiological confirmation
Patients able to provide informed consent and follow all the study procedures as indicated by the protocol
Informed Consent as documented by signature

Exclusion criteria

Younger than 44 years old or older than 81 years old included
Known drug or alcohol abuse
Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc.
Participation in another study with an investigational drug within the 30 days preceding and during the present study
Treatment with an injective approach in the previous 3 month
Surgical treatment in the previous 12 months.