A Study to Evaluate Coronary Atherosclerosis in Patients With Diabetes Mellitus (DREAM-CCTA)

Asan Medical Center

Status: Enrolling

Conditions: Diabetes Mellitus

Study type: Observational

Funder types: Other

Identifiers

NCT05801432

2021-0759

Details and patient eligibility

About

The purpose of this study is to evaluate the natural history of coronary atherosclerosis development and progression over time by CCTA and to identify risk factors attributable to the development of coronary atherosclerosis in a Korean DM population.

Full description

Patients with diabetes mellitus, who underwent initial CCTA (coronary computed tomographic angiography) at the Diabetes Center of the Asan Medical Center between February 2008 and June 2012, will be evaluated for inclusion in the study. All DREAM-CCTA study patients will undergo follow-up CCTA based on order from their primary physician. CCTA and demographic data, medical history, cardiovascular risk factors, and laboratory data was collected in case report forms at the time of the initial CCTA and at the time of follow-up CCTA.

Enrollment: 511 estimated patients

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 19 years or older
• Asymptomatic patients with type 2 DM who had undergone initial CCTA evaluation at the Diabetes Center of the Asan Medical Center between February 2008 and June 2012
• Willing and able to provide informed written consent

Exclusion criteria

• Blood test results that the Creatinine level exceeds 1.5 mg/dL
• A person with a history of anaphylaxis or allergic shock associated with a contrast medium
• Pregnant women
• Unable to undergo follow-up CCTA
• Uninterpretable CCTA