A Study to Evaluate the Safety and Efficacy of an Investigational Drug in the Treatment of Postoperative Dental Pain (MK-2295-005)

Merck Sharp & Dohme (MSD)

Status and phase: Completed; Phase 2

Conditions: Tooth Extraction; Pain, Postoperative

Treatments: Drug: MK2295

Study type: Interventional

Funder types: Industry

Identifiers

NCT00387140

2006_518

MK2295-005

2295-005

Details and patient eligibility

About

This study is being conducted to evaluate the safety and tolerability of the drug and to evaluate its efficacy compared to placebo and to ibuprofen in the treatment of postoperative dental pain in male patients.

Enrollment: 89 patients

Sex: Male

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients in generally good health who are scheduled to have two or more third molars removed, at least one of which is partially or completely embedded in bone and is a mandibular impaction

Exclusion criteria

• Patient has a temperature of 37.5C or greater prior to dosing
• Patient has participated in another clinical study within the last 4 weeks

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind