A Study to Explore the Role of Gut Flora in COVID-19 Infection

ProgenaBiome

Status: Enrolling

Conditions: COVID-19; Corona Virus Infection; Gut Microbiome; Coronaviridae Infections; Coronavirus 19; COVID; Coronavirus-19; Gastrointestinal Microbiome; COVID 19; Coronavirus

Treatments: Other: There is no intervention in this study

Study type: Observational

Funder types: Other

Identifiers

NCT04359836

PRG-041

Details and patient eligibility

About

This study seeks to determine whether the virus which causes COVID-19, SARS-CoV-2, is shed in the stools of patients who are infected.

Full description

In this study the stool of patients who are being treated for COVID-19 will be tested during treatment and then again following treatment to determine if the virus is shed in the stool during infection, afterwards, or both.

Enrollment: 250 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Signed informed consent, demonstrating that the patient understands the procedures required for the study and the purpose of the study
2. Male or female of 18 years of age or older
3. Diagnosis of COVID-19 infection by RT- PCR within 1 week of Screening

Exclusion criteria

1. Refusal to sign informed consent form
2. History of bariatric surgery, total colectomy with ileorectal anastomosis or proctocolectomy.
3. Postoperative stoma, ostomy, or ileoanal pouch
4. Treatment with total parenteral nutrition

Trial design

250 participants in 1 patient group

General Population

Description:

The general population will have their microbiome sequenced from stool samples provided.

Treatment:

Other: There is no intervention in this study