A Study Using Human Papillomavirus (HPV) DNA Testing to Detect HPV-Related Oropharyngeal Cancer (OPC)

Memorial Sloan Kettering Cancer Center (MSK)

Status: Active, not recruiting

Conditions: HPV-Related Carcinoma; Oropharyngeal Cancer; HPV Positive Oropharyngeal Squamous Cell Carcinoma

Treatments: Diagnostic Test: NavDx

Study type: Observational

Funder types: Other

Identifiers

NCT05814549

22-234

Details and patient eligibility

About

The researchers think that a blood test (NavDx®) may be able to identify cancer early by looking for circulating DNA from Human Papillomavirus/HPV. Circulating DNA are small pieces of genes that are released into the bloodstream. The purpose of this study is to find out whether using this blood test to test for HPV DNA will help detect HPV-related Oropharyngeal Cancer/OPC.

Enrollment: 9 patients

Sex: All

Ages: 45+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Ages 45 and older
• Self-reported history of four or more lifetime sexual partners
• Self-reported history of one or more lifetime oral sexual partner
• No previous history of diagnosed HPV-related head and neck cancer

Exclusion criteria

• History of diagnosed HPV-related OPC
• Less than three sexual partners in lifetime
• No history of oral sex performed
• Younger than age 45

Trial design

9 participants in 1 patient group

No previous history of diagnosed HPV-related head and neck cancer

Description:

Participants have no previous history of diagnosed HPV-related head and neck cancer

Treatment:

Diagnostic Test: NavDx