a-tDCS Combined With Aerobic Exercise in Healthy Individuals

Marmara University

Status: Unknown

Conditions: Healthy

Treatments: Device: Real tDCS; Other: Exercise; Device: Sham tDCS

Study type: Interventional

Funder types: Other

Identifiers

NCT04211779

09.2019.669

Details and patient eligibility

About

The purpose of this study is to assess the effects on the exercise performance of anodal transcranial direct current stimulation combined with aerobic exercise in healthy individuals.

Full description

Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation method that has become increasingly popular in recent years. tDCS shows promising improvements for the motor performance of healthy individuals as well as pathological conditions. Moreover, it is frequently preferred because of its safety advantage, high tolerability as well as being cheap, portable and easily applicable.

Studies have shown that tDCS can modulate the excitability of both cortical and subcortical brain regions. In recent years, there have been scientific studies investigating the effects of tDCS on improving physical performance in healthy individuals, but these studies are limited in number, their results are conflicted and as far as the investigators know there is no study that combines tDCS with exercise.

Moreover, although the mechanisms of tDCS on physical performance are largely unknown, some tDCS devices are open to public usage and a large number of professional athletes have reported using tDCS during their training programs. Therefore, studies are needed to demonstrate the effects of tDCS which combined with exercise on performance.

The aim of this study was to investigate the effects of anodal transcranial direct current stimulation combined with aerobic exercise on physical performance in healthy individuals.

Enrollment: 21 estimated patients

Sex: Male

Ages: 20 to 25 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy subject
• No use of any ergogenic substance in one year
• No history of active exercise training in last 6 months

Exclusion criteria

• Pacemaker
• Intracerebral metallic implant
• Using dietary supplementation or medication potentially affecting the CNS
• Musculoskeletal injury within the past 6 weeks
• Lower extremity pain above 3 or more according to numeric pain scale
• History of epilepsy or convulsive crisis

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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21 participants in 3 patient groups

Real tDCS and Exercise

Experimental group

Description:

tDCS (tDCS - TCT Research Limited, Hong Kong) / Exercise Group in which will receive the active intervention of aerobic exercise training and active tDCS intervention at the same time.

Treatment:

Other: Exercise

Device: Real tDCS

Sham tDCS and Exercise

Sham Comparator group

Description:

Sham tDCS (tDCS - TCT Research Limited, Hong Kong) / Exercise Group in which will receive the active intervention of aerobic exercise training and sham tDCS intervention at the same time.

Treatment:

Other: Exercise

Device: Sham tDCS

Exercise

Other group

Description:

Exercise group in which will receive the active intervention of aerobic exercise training no tDCS intervention.

Treatment:

Other: Exercise