A Test of Iron Malabsorption in Patients With Iron Deficiency Anemia

National Institutes of Health (NIH)

Status and phase: Completed; Phase 1

Conditions: Iron Deficiency Anemia

Treatments: Drug: stable isotope of iron, dysprosium

Study type: Interventional

Funder types: NIH

Identifiers

NCT00399191

R43 DK64495 (completed)

Details and patient eligibility

About

The objective of the study is to develop a simple, noninvasive test for evaluation of iron absorption as a tool to determine the cause of iron deficiency anemia. Healthy, premenopausal women with iron deficiency with or without anemia will be recruited for the study. Participants will, over the course of two months, ingest an iron solution three times; after each iron ingestion, participants will collect their stool and bring it to the study investigators for assessment of iron content.

Enrollment: 15 estimated patients

Sex: Female

Ages: 20 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ferritin <40

Exclusion criteria

• pregnant,
• post-partum,
• s/p GIT surgery,
• known malabsorption,
• coeliac disease,
• Helicobacter pylori

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)