A Training of the Rhythmic Skills With a Serious Game to Improve Gait and Cognitive Abilities in Parkinson's Disease (RGP)

University Hospital Center (CHU)

Status: Suspended

Conditions: Parkinson Disease

Treatments: Other: Rhythm workers training Perceptive timing; Other: No Rhythm workers training; Other: Rhythm workers training sensorimotor timing

Study type: Interventional

Funder types: Other

Identifiers

NCT02855710

9499

Details and patient eligibility

About

This project aims at assessing the opposite relation, namely the effect of a training of the general timing abilities on gait in Parkinson's disease. Timing rehabilitation will be done by the means of a serious game. Serious games are more and more used to improve the compliance and the efficacy of reeducaiton programs. Overall, we propose to test a low-cost tool for rehabilitation.

Full description

Auditory rythmic cueing is a method consisting in presenting a regular auditory stimulus (metronom or music) when someone is walking. It is known to improve gait in pathologies such as Parkinson's disease. It has also an effect on general timing abilities (e.g. tapping the beat of the music). This project aims at assessing the opposite relation, namely the effect of a training of the general timing abilities on gait in Parkinson's disease. Timing rehabilitation will be done by the means of a serious game. Serious games are more and more used to improve the compliance and the efficacy of reeducaiton programs. Overal, we propose to test a low-cost tool for rehabilitation.

Enrollment: 35 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age < 18
• good understanding of the nature, the goal and the methodology of the study
• signing of the informed consent
• being insured with a social security
• Diagnostic of idiopathic Parkinson's disease following the Queen Square Brain Bank (Hughes, 1992)
• Hoehn et Yahr between 2 and 3
• mild to moderate walk and speech deficits (Item MDS-UPDRS)
• stable therapy one month before inclusion for all the duration of the study

Exclusion criteria

• Atypic Parkinson Syndrom (oculomotor troubles, early falls, hallucinations, MoCA<20, early dysautonomy)
• dystonia ou dyskinesia preventing from using a tablet (item MDS-UPDRS4.2 >2)
• Unable to move without help (walking stick, walker, wheelchair) (item MDS-UPDRS 2.12 >2)
• adult protected by law
• deprivation of liberty
• High propability of non compliance to the protocol
• pregnant women, nursing women
• moderate to severe auditory trouble
• Severe walk fluctuations item MDS-UPDRS 4.4 >2)
• Pacemaker or neurosensorial device or heart defebrillator
• Cochlear implants
• ferromagnetic external bodies claose to the brain
• Metallic prothesis
• agitated, non cooperative patient
• claustrophobic patient
• neuro-surgical shunt valves
• dental appliance

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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35 participants in 4 patient groups

No training

Other group

Description:

Parkinsonian Patients with no Rhythm Workers training perceptive timing and senrorimotor timing

Treatment:

Other: No Rhythm workers training

Perceptive timing training

Other group

Description:

Parkinsonian Patients with Rhythm Workers training perceptive timing

Treatment:

Other: Rhythm workers training Perceptive timing

Sensorimotor timing training

Other group

Description:

Parkinsonian Patients with Rhythm Workers training sensorimotor timing

Treatment:

Other: Rhythm workers training sensorimotor timing

Healthy volunteers

Other group

Description:

Healthy people with Rhythm Workers training perceptive timing

Treatment:

Other: Rhythm workers training Perceptive timing