A Trial Comparing High-flow Nasal Oxygen With Standard Management for Conscious Sedation During Endoscopic Retrograde Cholangiopancreatography in Prone Position

Yonsei University

Status: Completed

Conditions: Patients Undergoing Endoscopic Retrograde Cholangiopancreatography in Prone Position

Treatments: Biological: high-flow humidified oxygen-delivery system (OptiFlow THRIVE)

Study type: Interventional

Funder types: Other

Identifiers

NCT03872674

1-2018-0082

Details and patient eligibility

About

Traditional conscious sedation for endoscopic retrograde cholangiopancreatography in prone position places patients at risk of desaturation, and high-flow nasal oxygen may reduce the risk. The aim of this study is to evaluate the role of high-flow nasal oxygen during endoscopic retrograde cholangiopancreatography. The investigators will compare the lowest SpO2 of standard nasal oxygen cannula group and that of high-flow humidified oxygen-delivery system group during the procedure.

Enrollment: 72 patients

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 1. patients who will undergo endoscopic retrograde cholangiopancreatography under conscious sedation

Exclusion criteria

• 1. dementia or cognitive dysfunction
• 2. altered mental status
• 3. intubated patients or tracheostomy
• 4. pregnancy
• 5. recent history of nasal bleeding
• 6. illiteracy or foreigner

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

72 participants in 2 patient groups

standard oxygenation(nasal cannula)

No Intervention group

Description:

stand oxygenation arm will receive oxygen at 5 L/min via nasal cannula

high-flow humidified oxygen-delivery system(OptiFlow THRIVE)

Experimental group

Description:

Optiflow THRIVE arm will receive oxygen at 50 L/min via Optiflow THRIVE

Treatment:

Biological: high-flow humidified oxygen-delivery system (OptiFlow THRIVE)