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30% of ARDS patients ventilated according to NIH protocol presents CT scan evidence of hyperinflation. Functional analysis of pressure-time curve (Stress Index=SI) has been shown to identify this condition in experimental settings. We tested the hypothesis that the SI is an accurate predictor of mechanical stress due to overdistention in ARDS patients.
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The study presents two parts : a preliminary validation study and a clinical study.
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V. M. Ranieri, MD; P. Terragni, MD
Data sourced from clinicaltrials.gov
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