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A Virtual Reality Study of Cognitive Biases in Body Dysmorphic Disorder

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Mass General Brigham

Status

Completed

Conditions

Healthy
Body Dysmorphic Disorders

Treatments

Other: Virtual reality experience

Study type

Observational

Funder types

Other

Identifiers

NCT03773549
2018P001894

Details and patient eligibility

About

Previous research shows that individuals with Body Dysmorphic Disorder (BDD) misinterpret ambiguous social information in a negative and threatening manner. These erroneous threat appraisals are thought to maintain disorder symptomatology and psychosocial impairment by reinforcing individuals' distorted self-image and ideas of social undesirability. Thus, maladaptive interpretation biases represent an important treatment target for this population; however, existing bias assessments and modification protocols are limited by the hypothetical and distal nature of scenarios and do not capture momentary experiential threat processes. The proposed study seeks to test virtual reality (VR) technology as a novel, in vivo means of eliciting, identifying, and measuring threat interpretation biases in a clinical sample to better understand the fear/threat structure activated during social interactions in BDD. Findings have the potential to enhance our understanding of disorder maintenance and identify more nuanced treatment targets. This study represents a critical first step in the long-term goal of harnessing VR gaming technology to supercharge existing treatment approaches for this debilitating illness.

Enrollment

58 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Age 18+,
  • Fluent in English,
  • Meet DSM-5 criteria for principal BDD (BDD group) or no other current psychiatric diagnosis (HC group; assessed via clinical interview).

Exclusion criteria

  • Lifetime psychosis; current bipolar disorder in acute or hypomanic episode; current severe substance use disorder; acute, active suicidal ideation
  • Intellectual disability or cognitive impairment that would interfere with participation

Trial design

58 participants in 2 patient groups

Body dysmorphic disorder
Description:
Meet DSM-5 criteria for principal body dysmorphic disorder, assessed via the Structured Clinical Interview for the DSM-V Axis I Disorders (SCID)
Treatment:
Other: Virtual reality experience
Healthy control
Description:
Individuals who do not have a current psychiatric diagnosis, assessed via the Mini-International Neuropsychiatric Interview (MINI)
Treatment:
Other: Virtual reality experience

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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