A Warmer Temperature Decrease Propofol Injection Pain

Xingui Dai

Status: Unknown

Conditions: Temperature Change, Body; Injection Site Irritation; Propofol Syndrome

Treatments: Behavioral: warmer temperature

Study type: Interventional

Funder types: Other

Identifiers

NCT03420560

Warm Decrease Pain

Details and patient eligibility

About

Propofol injection pain will be surfed by up to 70-80 percentage by the Patients who induced by propofol. Temperature of Operating room was set to a certain range in normal clinical practice, which is 22- 26 centigrade. Warm feeling will make skin vassal dilated and more blood will pass through to bring more heat out of our body. It had been reported that a bigger venous vessels will get less propofol injection pain.

The investigators hypothesis that Patients who stayed in a warmer room temperature will surf less injection pain while compare to a normal setting room temperature.

Enrollment: 120 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA I~III, aged 18，scheduled or emergency surgery with general anesthesia.

Exclusion criteria

• a history of allergy to propofol, allergy to soybean oil
• with peripheral blood diseases.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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120 participants in 2 patient groups, including a placebo group

warmer temperature

Experimental group

Description:

To compare the incidence and intensity of pain on injection that is caused by propofol in warm temperature（27℃） versus normal temperature(23℃).

Treatment:

Behavioral: warmer temperature

normal temperature

Placebo Comparator group

Description:

The purpose of this study is to compare the incidence and intensity of possible pain on injection as well as patient satisfaction caused by propofol in different room temperature(27 VS 23).

Treatment:

Behavioral: warmer temperature