AAA Rupture Risk Assessment in COVID-19 Pandemic

Masaryk University

Status: Unknown

Conditions: COVID-19; Abdominal Aortic Aneurysm

Treatments: Diagnostic Test: Biomechanical rupture risk assessment

Study type: Observational

Funder types: Other

Identifiers

NCT05197543

BRRA19

Details and patient eligibility

About

The acute phase of the COVID-19 pandemic requires a redefinition of healthcare system to increase the number of available intensive care units for COVID-19 patients. This leads to the postponing of elective surgeries including the treatment of abdominal aortic aneurysm (AAA). The probabilistic rupture risk index (PRRI) recently showed its advantage over the diameter criterion in AAA rupture risk assessment. Its major improvement is in increased specificity and yet has the same sensitivity as the maximal diameter criterion. The objective of this study was to test the clinical applicability of the PRRI diagnostic method in a quasi-prospective observational patient cohort study.

Enrollment: 102 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• presence of asymptomatic abdominal aortic aneurysm (AAA)
• regular CT angiography scans available

Exclusion criteria

• rupture of AAA

Trial design

102 participants in 2 patient groups

BRRA group

Description:

Rupture risk of asymptomatic AAAs in this group was estimated using Biomechanical rupture rist assessment (BRRA). BRRA considers an AAA as a pressure vessel and estimates its risk of rupture by comparing its wall stress to wall strength

Treatment:

Diagnostic Test: Biomechanical rupture risk assessment

Maximal diameter group

Description:

Rupture risk of asymptomatic AAAs in this group was estimated by a classical approach based on a maximal diameter.