Abbreviated Breast MRI (AB-MRI) With Golden-angle Radial Compressed-sensing and Parallel Imaging (GRASP)

NYU Langone Health

Status: Active, not recruiting

Conditions: Breast Cancer

Treatments: Diagnostic Test: Breast Imagers; Diagnostic Test: Predictive Model

Study type: Observational

Funder types: Other

Identifiers

NCT03927768

18-00684

Details and patient eligibility

About

The purpose of this study is to use a magnetic resonance imaging (MRI) sequence called golden-angle radial compressed sensing and parallel imaging (GRASP) as a noninvasive and fast way to measure the wash-in contrast (dye) in the breast. MRI uses a strong magnetic field and radio waves to create images of structures in the body. The goal is to determine if benign and malignant breast lesions have different patterns of contrast wash in.

This study will ask woman planning to undergo a clinical breast MRI with contrast (dye) as part of their standard care.

Enrollment: 264 patients

Sex: Female

Ages: 18 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• No contraindications to MRI scanning (pacemaker, implanted metallic objects, severe obesity or other condition that leads to difficulty lying in the magnet)
• Able and willing to provide informed consent

Exclusion criteria

• Currently undergoing neoadjuvant chemotherapy for breast cancer treatment.

Trial design

264 participants in 2 patient groups

200 women undergoing clinical breast MRI

Description:

At time of previously scheduled clinical breast MRI, 60 second postcontrast imaging sequence will be added to the clinical breast MRI. MRI will be interpreted according to usual departmental protocols.

Treatment:

Diagnostic Test: Predictive Model

Diagnostic Test: Breast Imagers

50 women undergoing clinical breast MRI

Description:

At time of previously scheduled clinical breast MRI, 60 second postcontrast imaging sequence will be added to the clinical breast MRI. MRI will be interpreted according to usual departmental protocols.

Treatment:

Diagnostic Test: Predictive Model

Diagnostic Test: Breast Imagers