Abbreviated MRI for HCC Surveillance

Seoul National University

Status: Active, not recruiting

Conditions: Chronic Hepatitis; Liver Cirrhosis; Hepatocellular Carcinoma

Treatments: Diagnostic Test: Biannual ultrasonography; Diagnostic Test: Annual abbreviated liver MRI

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT03731923

SNUH-2018-1426

Details and patient eligibility

About

This study aims to investigate the clinical feasibility of abbreviated liver MRI for HCC surveillance in a high-risk group.

Enrollment: 257 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• high risk of HCC development (chronic hepatitis B, chronic hepatitis C, liver cirrhosis)
• no history of HCC
• on surveillance of HCC using ultrasonography
• sign informed consent

Exclusion criteria

• history of HCC
• congestive hepatopathy
• iron deposition
• any absolute or relative contra-indication of contrast-enhanced MRI

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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257 participants in 1 patient group

High risk group of HCC

Experimental group

Description:

High risk group of HCC with chronic hepatitis or liver cirrhosis. Participants undergo biannual ultrasonography and annual abbreviated liver MRI.

Treatment:

Diagnostic Test: Annual abbreviated liver MRI

Diagnostic Test: Biannual ultrasonography