Ablation of Ventricular Fibrillation by Accurate Targeting of Arrhythmogenic Regions (AVATAR)

University of California San Diego

Status: Completed

Conditions: Ventricular Tachyarrhythmias

Study type: Observational

Funder types: Other

Identifiers

NCT01492764

AVATAR

Details and patient eligibility

About

This study will test the hypothesis that many human heart rhythm disorders are caused by small localized sources, where brief ablation may successfully eliminate the heart rhythm disorder.

Full description

The investigators will enroll patients with documented rapid heart rates from the bottom chambers of the heart (ventricular tachyarrhythmias).

During electrophysiological study, the investigators will map the localized sources of these heart rhythm disorders.

1. The 'active' group will prospectively receive brief ablation at localized sources (Focal Impulse and Rotor Modulation, FIRM).
2. The control group will be a historical cohort who have received traditional ablation for this disorder.

All patients will be followed for up to 1 year to ensure that they have no recurrent arrhythmias.

Enrollment: 2 patients

Sex: All

Ages: 21 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Documented ventricular tachyarrhythmias.
2. Undergoing clinically indicated EP study with ablation.

Exclusion criteria

1. Unwillingness or inability to provide informed consent.

Trial design

2 participants in 2 patient groups

Active Group

Description:

This group will receive brief ablation at localized sources (Focal Impulse and Rotor Modulation, FIRM)

Control Group

Description:

This group receives traditional ablation for this disorder