Abnormal Pain Processing in COPD Patients

University of Granada (UGR)

Status: Unknown

Conditions: Pulmonary Disease, Chronic Obstructive; Pain

Study type: Observational

Funder types: Other

Identifiers

NCT04319523

DF0087UG

Details and patient eligibility

About

Dyspnea, cough, and fatigue are the symptoms characteristic of moderate-severe COPD. Within the progression of disease was also reported a prevalence of 34-77% of pain symptoms in these patients. A review observed a higher score in pain intensity/interference associated with multiples pain locations of COPD patients. Pain in chronic diseases may appear to result from abnormalities in pain processing because of the damage and/or inflammation of peripheral structures.

Full description

Dyspnea, cough, and fatigue are the symptoms characteristic of moderate-severe COPD. Within the progression of disease was also reported a prevalence of 34-77% of pain symptoms in these patients. A review observed a higher score in pain intensity/interference associated with multiples pain locations of COPD patients. Several studies reported that comorbidities, GOLD grade, and breathlessness may contribute to a higher pain prevalence in COPD patients because of the systemic inflammatory process and lung hyperinflation. Pain in chronic diseases may appear to result from abnormalities in pain processing and alteration of sensitization due to the damage and/or inflammation of peripheral structures.

Enrollment: 65 estimated patients

Sex: All

Ages: 50+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Between 50 and older age
• Accepted to sign the informed consent

Exclusion criteria

• comorbidities with a course of chronic pain that interfered with evaluation
• the presence of cognitive impairment to understand the questionnaire

Trial design

65 participants in 2 patient groups

COPD patients

Healthy subjects