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Abnormalities of B Lymphocytes During Systemic Lupus

U

University Hospital, Strasbourg, France

Status

Completed

Conditions

Systemic Lupus Erythematosus

Treatments

Procedure: Blood samples

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

Previous experimental data strongly suggest that B lymphocytes have intrinsic abnormalities during lupus in mice spontaneously affected by the disease. This study tries to define these abnormalities by looking at the gene expression profile of purified B lymphocytes from patients with non active systemic lupus , compared with the gene expression profile of purified B lymphocytes from healthy donnors.

Enrollment

30 estimated patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • non active systemic lupus

Exclusion criteria

  • immunosuppressive drugs
  • more than 10 mg of prednisone per day

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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