Acclimatization Mechanisms During Ascent to 7500m

University of Zurich (UZH)

Status: Completed

Conditions: Acute Mountain Sickness

Treatments: Behavioral: ascent protocol

Study type: Interventional

Funder types: Other

Identifiers

NCT00603122

EK-1189

SNSF 3200B0-108300

Details and patient eligibility

About

The trial evaluates the role of ascent protocol on acute mountain sickness and cardio-respiratory physiology during an ascent to Muztagh Ata (7546m). Two groups of mountaineers ascend with different acclimatization time to the summit. The prevalence and severity of symptoms of acute mountain sickness are evaluated along with physiologic variables.

Enrollment: 37 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy, physically fit subject
• Mountaineering experience

Exclusion criteria

• Any type of cardiac or respiratory disease
• Regular intake of any medication
• History of high altitude pulmonary oedema
• Severe acute mountain sickness at altitudes below 3500m or high altitude cerebral oedema.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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37 participants in 2 patient groups

1

Experimental group

Description:

fast ascent

Treatment:

Behavioral: ascent protocol

2

Active Comparator group

Description:

slow ascent

Treatment:

Behavioral: ascent protocol