According CTC to Compare the Influences of Different Methods to Remove the PDAC

Fudan University

Status: Unknown

Conditions: Carcinoma, Pancreatic Ductal; Circulating Tumor Cells

Treatments: Procedure: routine surgery; Procedure: no-touch surgery; Procedure: laparoscopic surgery

Study type: Interventional

Funder types: Other

Identifiers

NCT02451384

B2015-010

Details and patient eligibility

About

Acccording circulating tumor cells to compare the differences of different methods(routine method、no-touch principle method、laparoscopy method) to remove the ductal adenocarcinoma of pancreatic body and tail.

Enrollment: 45 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Ductal adenocarcinoma of pancreatic body and tail
• Tumor can be removed
• No other tumors and without liver metastases
• Age from 18 to 80 years old

Exclusion criteria

• Neoplasms with other sites of the pancreas
• With other tumors of any other sites

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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45 participants in 3 patient groups

routine surgery

Experimental group

Description:

In this arm the patients will be performed routine surgery to remove the tumors. And then we compare their circulating tumor cell countings in the pre and post-operation.

Treatment:

Procedure: routine surgery

no-touch surgery

Experimental group

Description:

In this arm the patients will be performed no-touch surgery to remove the tumors. And then we compare their circulating tumor cells countings in the pre and post-operation.

Treatment:

Procedure: no-touch surgery

laparoscopy surgery

Experimental group

Description:

In this arm the patients will be performed laparoscopy surgery to remove the tumors. And then we compare their circulating tumor cells countings in the pre and post-operation.

Treatment:

Procedure: laparoscopic surgery