Accuracy of PoCT to ELISA by Detecting Human IL-6 in Teeth with Apical Periodontitis (PoCT ELISA)

Manipal University College Malaysia

Status: Not yet enrolling

Conditions: Apical Periodontitis

Treatments: Device: Point of Care Test

Study type: Observational

Funder types: Other

Identifiers

NCT06701266

MUCM/005D/11/2024

Details and patient eligibility

About

To compare the diagnostic agreement of human IL-6 chairside PoCT to ELISA in apical periodontitis undergoing endodontic therapy which could be clinically helpful to monitor the healing of periapical tissues enabling the clinician to complete the endodontic procedure, leading to a better patient care.

This study will be conducted at the Conservative and Endodontics Department in Polyclinic B, Faculty of Dentistry, Manipal University College Malaysia (MUCM). It involves 30 selected patients who have single rooted tooth with apical periodontitis that undergo RCT. The collection of the exudate from the canal will be on pre and post-instrumentation. The exudated will collect twice in each instrumentation for PoCT and ELISA.

Enrollment: 30 estimated patients

Sex: All

Ages: 17 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient having single root tooth with AP that is negative to the pulp sensitivity test
• Presence of periapical lesion

Exclusion criteria

• Pregnancy

Trial design

30 participants in 1 patient group

Patient have apical periodontitis

Description:

Patient have single rooted tooth with apical periodontitis that undergo RCT in MUCM.

Treatment:

Device: Point of Care Test