Accuracy of Pre-existing Risk Scoring Models for Predicting Acute Kidney Injury in Patients Who Underwent Aortic Surgery Using a Gray Zone Approach

Samsung Medical Center

Status: Completed

Conditions: Postoperative Acute Kidney Injury; Aortic Surgery

Treatments: Procedure: elective or emergency aortic surgery (including ascending, arch, descending thoracic aorta)

Study type: Observational

Funder types: Other

Identifiers

NCT01844219

2013-03-059-001

Details and patient eligibility

About

Acute kidney injury after cardiac surgery has been reported to increase morbidity and mortality. Several risk scoring models for prediction of aortic kidney injury after cardiac surgery have been developed. However, predictive accuracy of these models is stil unclear. The aim of this study is to evaluate the accuracy of four pre-existing prediction models using a gray zone approach in patients who underwent aortic surgery in our institution.

Full description

Acute kidney injury after cardiac surgery has been reported to increase morbidity and mortality. Several risk scoring models for prediction of aortic kidney injury after cardiac surgery have been developed. However, predictive accuracy of these models is stil unclear. The aim of this study is to evaluate the accuracy of four pre-existing prediction models (AKICS, Wijeysundera, Mehta, and Thakar model)using a gray zone approach in patients who underwent aortic surgery in our institution. Based on receiver operating characteristic (ROC) curve analysis, we will construct a gray zone using the cut-off values with a sensitivity of < 90%, and a specificity of < 90% (diagnostic tolerance of 10%).

Enrollment: 375 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Those who underwent elective or emergency aortic surgery in Samsung Medical Center during between 2004 and 2010.

Exclusion criteria

• missing laboratory data
• preoperative hemodialysis
• death during or within 48 hours after surgery

Trial design

375 participants in 1 patient group

Patients who underwent aortic surgery

Description:

Patients who underwent aortic surgery in Samsung Medical Center during the period between 2004 and 2010

Treatment:

Procedure: elective or emergency aortic surgery (including ascending, arch, descending thoracic aorta)