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Accuracy of Zero Heat Flux Cutaneous Temperature in Intensive Care Adults (TempCore)

P

Poitiers University Hospital

Status

Completed

Conditions

Arterial Temperature
Zero Heat Flux Method
Esophageal Temperature
Continuous Non Invasive Cutaneous Temperature
Intracerebral Temperature

Treatments

Procedure: intracerebral temperature
Procedure: esophageal temperature
Procedure: arterial temperature
Procedure: temperature obtained by the non-invasive method of zero-heat flux

Study type

Interventional

Funder types

Other

Identifiers

NCT02931227
TempCore

Details and patient eligibility

About

Temperature is one of the vital signs usually monitored in patients of ICUs. Indeed, fever occurs frequently in ICU especially in brain injured patients and may require targeted temperature management (TTM) in special case as intracranial hypertension or post cardiac arrest. In ICU, non invasive device to monitor temperature are not recommended and only invasive ones are accurate enough for TTM. Arterial pulmonary temperature is still the gold standard, but esophageal device is currently used in ICU patients.

The goal of this study is to compare accuracy of a continuous noninvasive cutaneous temperature using zero-heat-flux (ZHF) method to esophageal temperature, arterial temperature and intracerebral temperature if present for clinical monitoring.

All adults patients admitted in the neurosurgical or surgical ICU are eligible for inclusion into this study.

Assessment of temperature will be continuously monitored by esophageal probe (MON-A-THERM, 12Fr, COVIDIEN, Dublin, Ireland) (Teso), ZHF sensor (SpotOn, 3M, St Paul, MN, USA) (TZHF) and, in patients requiring cardiac output monitoring, by femoral arterial catheter (Pulsiocath PICCO, PULSION, Munich, Germany) (Tart). The correct positioning of the esophageal probe will be controlled by chest X-ray. The ZHF temperature sensor (TZHF) will be placed on the forehead as recommend by the manufacturer and connected to the SpotOn monitor. Intra cerebral temperature (Tbrain) will be obtained with an intracranial probe used as calibrator for partial pressure of O2 in brain (PbO2, Licox®Combined Oxygen and Temperature Probe 462 mm device necessary for monitoring severe brain injured patients. The ZHF sensor will be changed every 24 hours according to the manufacturer's directions for use. Temperatures will be recorded automatically at a 5-minutes interval via the patient's monitor with an electronic data acquisition system (Data Collect, Phillips) for a maximum of 5 days.

For each patient included, data recorded will be: demographic and clinical particulars for each patient; information on hemodynamics, sedative, analgesic and inotropic agents, use of neuromuscular blockades and their indication, reason of hypo or hyperthermia (spontaneous or therapeutic), indication and the means used (neuromuscular blockades, external or internal cooling) in case of Targeted Temperature Management; complications related to the ZHF sensor application.

Enrollment

120 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • minimum 18 years old
  • patients who required core temperature monitoring

Exclusion criteria

  • front disrepair
  • refusal to participate

Trial design

Primary purpose

Other

Allocation

Non-Randomized

Interventional model

Single Group Assignment

Masking

None (Open label)

120 participants in 4 patient groups

Brain-injured group
Experimental group
Treatment:
Procedure: intracerebral temperature
Procedure: esophageal temperature
Procedure: temperature obtained by the non-invasive method of zero-heat flux
Hypothermia group
Experimental group
Treatment:
Procedure: intracerebral temperature
Procedure: esophageal temperature
Procedure: temperature obtained by the non-invasive method of zero-heat flux
Hyperthermia group
Experimental group
Treatment:
Procedure: intracerebral temperature
Procedure: esophageal temperature
Procedure: temperature obtained by the non-invasive method of zero-heat flux
PICCO group
Experimental group
Treatment:
Procedure: intracerebral temperature
Procedure: esophageal temperature
Procedure: arterial temperature
Procedure: temperature obtained by the non-invasive method of zero-heat flux

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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