Acellular Dermal Matrix Allograft Versus Free Gingival Graft

University of Sao Paulo

Status: Completed

Conditions: Gingiva Atrophy; Gingivitis

Treatments: Device: Acellular Dermal Matrix; Procedure: Control

Study type: Interventional

Funder types: Other

Identifiers

NCT03251001

BauruSchoolDentistryADM

Details and patient eligibility

About

The present split-mouth controlled randomized clinical trial aimed to evaluate clinical and histological results of acellular dermal matrix allograft (ADM) compared to autogenous free gingival graft (FGG)

Enrollment: 25 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• absence or deficiency of keratinized tissue (< 1mm) in two homologous contralateral sites of inferior premolars
• Miller Class I or II gingival recession
• Absence of radiographic bone loss
• Vital tooth or with adequate endodontic treatment
• Root surfaces without caries
• Good oral hygiene (plaque index < 20%)

Exclusion criteria

• Allergic to penicillin
• Presenting systemic disease that impede surgical procedure
• Smokers
• Pregnancy
• Intake of calcium channel blockers that cause gingival augmentation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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25 participants in 2 patient groups

Control

Active Comparator group

Description:

Sites receiving a free gingival graft

Treatment:

Procedure: Control

Device - Acellular dermal matrix

Experimental group

Description:

Sites receiving acellular dermal matrix

Treatment:

Device: Acellular Dermal Matrix