Acetic Acid Chromoendoscopy to Judge Gastric Intestinal Metaplasia (IM)

Konyang University Hospital

Status: Completed

Conditions: Metaplasia; Stomach Neoplasms

Treatments: Procedure: Acetic acid chromoendoscopy

Study type: Interventional

Funder types: Other

Identifiers

NCT01499576

11-62

Details and patient eligibility

About

The presence and the extent of gastric intestinal metaplasia(IM) is a good indicator of high risk group of gastric cancer. Many methods was developed to survey it, including multiple gastric biopsy or methylene blue chromoendoscopy. But they are not practical in the routine screening exam, limited by cost and accessibility. Spraying of acetic acid is commonly used in screening cervical cancer, to induce whitish discoloration of metaplastic mucosa. The investigators have confirmed such whitish discoloration is induced in gastric IM, with accuracy > 80% in a pilot study of the investigators. This prospective study will tell the accuracy, sensitivity and specificity of acetic acid chromoendoscopy for judging gastric IM.

Enrollment: 126 patients

Sex: All

Ages: 35 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Person who undergo gastroduodenoscopy
• Person who visit Konyang University Hospital

Exclusion criteria

• Bleeding diathesis
• History of stomach neoplasms
• History of upper gastrointestinal surgery

Trial design

Primary purpose: Screening

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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126 participants in 1 patient group

Acetic acid spraying

Experimental group

Treatment:

Procedure: Acetic acid chromoendoscopy