Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)

National Alliance for Sickle Cell Centers

Status: Enrolling

Conditions: Sickle Cell Trait

Treatments: Other: Biologic Specimen Collection

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT06071377

AUNT

Details and patient eligibility

About

The main purpose of this study is to create a longitudinal cohort of those with Sickle Cell Trait (SCT) to better understand the hematologic phenotype for those that carry HbS, assess for differences in those with varying quantities of HbS and assess for potential clinical complications of SCT.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Are willing to voluntarily participate and sign the study consent
2. Know/suspect they have SCT and are willing to get tested to confirm/learn about their SCT status
3. Adults ages 18 and older

Exclusion criteria

1. Unwilling to sign consent
2. Known end-stage renal disease or dialysis
3. Known SCD (including sickle cell-beta thalassemia)
4. People who do not have SCT

Trial design

1,000 participants in 1 patient group

Individuals with sickle cell trait

Treatment:

Other: Biologic Specimen Collection