Acid Base Balance of ICU Patients With Severe Hypoalbuminemia, Before and After an Albumin Infusion, Using Stewart Approach (STEWALB)

University Hospital, Clermont-Ferrand

Status: Unknown

Conditions: Stewart Approach for Acid Base Disorders; Hypoalbuminemia; Adult ICU Patient; Human Albumin Perfusion

Treatments: Other: stewart approach

Study type: Observational

Funder types: Other

Identifiers

NCT02288494

CHU-0204

Details and patient eligibility

About

The primary purpose was to describe the acid base balance of ICU patients with severe hypoalbuminemia using Stewart's approach for acid base disorders, before and after an human albumin perfusion.

Full description

Prospective study, for ICU patient with severe hypoalbuminemia < 20g/L, determining biological parameters from Stewart approach for acid base disorders (pH, SIDe, SIDa, SIG, Atot, PaCO2) before, and at 1hour, 2hours and 24 hours after a 200mL 20% human albumin perfusion (the consensus conference ANAES of 1995 recommands to correct hypoalbuminemia below 20g/L).

Clinical parameters (respiratory, haemodynamic, neurologic) were also collected at the same times.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• serum albuminemia < 20g/L
• adult ICU patient
• Arterial line

Exclusion criteria

• albumin allergy
• pregnancy
• congestive heart failure

Trial design

100 participants in 1 patient group

hypoalbuminemia

Description:

The primary purpose was to describe the acid base balance of ICU patients with severe hypoalbuminemia using Stewart's approach for acid base disorders, before and after an human albumin perfusion

Treatment:

Other: stewart approach