Acromegaly - Before and After Treatment

University of Aarhus

Status: Unknown

Conditions: Growth Hormone Treatment; Bone Diseases; Cardiovascular Diseases; Sleep Apnea; Acromegaly

Study type: Observational

Funder types: Other

Identifiers

NCT03431727

1-10-72-126-16

Details and patient eligibility

About

The aim of the study is to investigate sleep apnea, circulation and metabolism in acromegaly before and after surgery and/or medical treatment.

Full description

Acromegaly is a rare disease caused by a growth hormone (GH) producing pituitary adenoma. Surgery is primary treatment, whereas medical treatment with a somatostatin analogue (SA), which suppresses GH secretion and reduces tumour size, is used when surgery is insufficient or unfeasible. Acromegaly is associated with metabolic abnormalities which contributes to an increased morbidity and mortality if left untreated. To which extend these abnormalities reverses after treatment, and if treatment modality influences the outcome, remain elusive. The aim of the study is to investigate sleep apnea, circulation and metabolism in acromegaly before and after surgery and/or medical treatment

Enrollment: 20 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Recently diagnosed with acromegaly
• Age above 18
• Written consent

Exclusion criteria

• Pregnancy