Active Commuting To Improve Well-being and Health in Everyday Life (GO-ACTIWE)

University of Copenhagen

Status: Completed

Conditions: Overweight and Obesity

Treatments: Behavioral: Physical activity

Study type: Interventional

Funder types: Other

Identifiers

NCT01962259

ACTIWE-1

Details and patient eligibility

About

The aim of present randomized controlled trial is to evaluate the health effects of physical activity in transport and leisure time domains of everyday life and to develop durable physical activity regimens, i.e. to go from lifestyle intervention to daily lifestyle routine, in overweight individuals.

Subjects will be randomized to 1 of 4 groups. 1: Vigorous intensity leisure time physical activity, 2: Moderate intensity leisure time activity, 3: Active commuting by bicycle, or 4: a non-intervention control group

Enrollment: 188 patients

Sex: All

Ages: 20 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy
• No engagement in habitual structured physical activity
• Body mass index 25-35 kg/m2
• Body fat percentage >32% for women and >25% for men
• Maximum oxygen uptake (VO2max) <40 ml O2/kg/min for women and <45 ml O2/kg/min for men
• Ethnicity: Caucasian

Exclusion criteria

• Chronic use of medicine
• Smoking
• Fasting plasma glucose > 6,1 mmol/L
• Blood pressure > 140/90 mm Hg
• Abnormal resting and working ECG
• Parents or siblings with diagnosed type 2 diabetes
• For women: Follicle stimulating hormone (FSH) concentration > 35 milliunits/ml, pregnancy or planning of pregnancy within the coming year

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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188 participants in 4 patient groups

Vigorous intensity LTPA

Experimental group

Description:

Leisure time physical activity (LTPA): Exercise intensity: 70% of maximal oxygen uptake (VO2 max); Energy expenditure: Females: 1600 kcal/week; Males: 2100 kcal/week

Treatment:

Behavioral: Physical activity

Moderate intensity LTPA

Experimental group

Description:

Leisure time physical activity (LTPA): Exercise intensity: 50% VO2 max; Energy expenditure: Females: 1600 kcal/week; Males: 2100 kcal/week

Treatment:

Behavioral: Physical activity

Active commuting

Experimental group

Description:

Bicycling to/from work/school/university. No requirements for exercise intensity; Energy expenditure: Females: 1600 kcal/week; Males: 2100 kcal/week; Avg distance per day Females 9-15 km; Males 11-17 km

Treatment:

Behavioral: Physical activity

Control

No Intervention group

Description:

Receives no intervention.